Member 11 Subfamily B ATP Binding Cassette Transporter

ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).

Also Known As:

ATP Binding Cassette Transporter, Subfamily B, Member 11; ABCB11 Protein; ATP Binding Cassette Subfamily B Member 11; ATP Binding Cassette Transporter, Sub-Family B, Member 11; BSEP Protein; Bile Salt Export Pump

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
  - Carrier Proteins: 13306
    - Membrane Transport Proteins: 606
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
      - Ion Pumps: 63
        Anion Transport Proteins: 2
        Organic Anion Transporters: 381
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
    - Membrane Transport Proteins: 606
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282
      - Ion Pumps: 63
        Anion Transport Proteins: 2
        Organic Anion Transporters: 381
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 11 Subfamily B ATP Binding Cassette Transporter: 282

Uta Synal-Hermanns Selected Research

Uta Synal-Hermanns Research Topics

Disease

Drug/Important Bio-Agent (IBA)